产品货号:
Z32477
中文名称:
Apolipoprotein AI/APOA1抗体
英文名称:
Anti-Apolipoprotein AI/APOA1 Antibody (Clone#17G5)
产品规格:
100μg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Apolipoprotein AI/APOA1 Antibody (Clone#17G5) |
指标别名 | Apo AI;ApoA I;APOA1;apolipoprotein A I;Apolipoprotein A1 |
克隆性 | Monoclonal |
检验物种 | human |
应用范围 | ELISA(Cap) |
基因名称 | APOA1 |
克隆号 | 17G5 |
抗体来源 | Mouse |
抗体类型 | IgG1 |
免疫原 | E.coli-derived mouse Apolipoprotein A I recombinant protein (Position:D25-Q264).Mouse Apolipoprotein A I shares 64% and 68.6% amino acid (aa) sequence identity with human and rat Apolipoprotein A I,respectively. |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | protein G purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Apolipoprotein A-1,also known as APOA1,is a human protein with a specific role in lipid metabolism.It binds to lipopolysaccharide or endotoxin,and has a major role in the anti-endotoxin function of HDL.The gene is mapped to 11q23.And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence.The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion.It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters.ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor,and thus may have an anticlotting effect.Defects in the gene encoding it are associated with HDL deficiencies,including Tangier disease,and with systemic non-neuropathic amyloidosis.Additionally,ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport. |
Uniprot ID | P02647 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (ZN1928) for Western blot,and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (ZN1866) for IHC(P) and ICC. |
推荐稀释比 | ELISA(Cap) 1:50~1:200 |
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